Gloriosa Fill

200 mg in vial
Gloriosa Fill - an innovative collagen stimulator based on polylactic acid allows you to restore the structure and function of the dermis, stimulating the natural formation of collagen in the skin.


Main ingredients: Poly-L-Lactic acid (PLLA) - 41% - 82 mg, CMC - carboxymethylcellulose - 24% - 48 mg, Mannitol - 35% - 70mg
Indications for use: correction of age-related changes in the skin of the face (temples, cheeks, cheekbones, soft tissues of the chin, parotid area, earlobes), correction of the relief of the skin of the face, neck, neckline increase and/or restoration of the volume of individual parts of the soft tissues of the face: cheek-zygomatic area, lower third of the face, temporal region; correction of age-related changes and creation of additional volume on the back surface of the hands; skin defects: bumpy skin texture, post-acne, atrophic scars, stretch marks; changes in body contours (ptosis, sagging skin on the abdomen, thighs, arms)
Mode of application: the drug is injected deep into the skin or subcutaneous layer using a needle or cannula. After injections, the treated area is massaged to ensure uniform distribution of the drug
Packing: 200 mg in vial
Storage conditions: at room temperature
Expiration date: 2 years
autoimmune diseases or undergoing autoimmune therapy
cancer, chemotherapy or radiation therapy
hemorrhagic syndrome, taking anticoagulants and drugs that reduce blood clotting
epilepsy and mental illness
viral or infectious diseases, herpes in the acute stage
acute inflammatory diseases or manifestations of chronic skin diseases in the area of proposed injections
hypersensitivity or allergic reaction to the components of the drug
tendency to form keloids
pregnancy and breastfeeding period

Gloriosa Fill is an innovative rejuvenation procedure that allows you to restore the structure and function of the dermis by stimulating the natural formation of collagen in the skin. Gloriosa Fill is based on poly-L-lactic acid, obtained in laboratory conditions by double lyophilization. Consists of a lyophilized powder consisting of microparticles of L-isomer polylactic acid, carboxymethylcellulose and pyrogenic mannitol. Gloriosa Fill particles have a smooth surface and a rounded shape, without sharp edges, which reduces the risk of uncontrolled inflammation. They also have a porous surface, allowing for better tissue integration and fibroblast fixation. GLORIOSA FILL microparticles have a diameter of 30 to 50 micrometers. After introduction into the tissue, polylactic acid starts a chain reaction: the acid activates fibroblasts, fibroblasts actively produce collagen and elastin fibers, and heteropolysaccharides - hyaluronic acid - are actively released in the intercellular matrix. Thanks to the effect on fibroblasts, the production of more of its own collagen is actively stimulated and a strong and, importantly, natural collagen framework is created in the tissues. The effect on the main cells - fibroblasts - leads to increased synthesis of all components of the extracellular matrix, restoration of regulatory, trophic and metabolic processes. Clinically, this is accompanied by an increase in skin elasticity, an improvement in its visco-elastic characteristics, which leads to the smoothing of fine wrinkles, a decrease in the depth of folds and creases, and a decrease in the severity of gravitational ptosis.

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